I used to add a quart of diesel fuel to the tank of my old carbureted non-catalytic converter car. It seemed to make it run better, but that is purely anecdotal. Granddad did this with the combine during harvesting season, claimed it gave it more power. Might be more believable there, due to that old machine having a big old low-compression 6-cylinder engine.
Another anecdotal potion is 1-2 oz. of xylene in a 20 gallon tank (tried it on a carbureted 1987 chrysler 5th avenue, did not seem to matter).
Then there are the rumored mothballs and/or benzene.. but that was for octane boosting in high compression engines and would not help the low-compression gasser MV engine much.
Lately, there are the "HHO" electrolyzers, but these things that are sold as kits are too weak. To work (make enough hydrogen and oxygen mixture to help the fuel burn better), it would need to be fed on the order of 100 amps, not the 10 amps the kits usually use (sometimes the electrolysis tank can explode as well). The HHO welder's inventor's site shows results using 100 amps at 12V. He 'apparently' got more fuel mileage out than extra DC power in, due to the sufficient volume of gas making the fuel burn alot better.
Alcohol has only about half the energy of gasoline, so adding it, unless it's free, would be of little value.
Best bet is probably to keep the spark hot, the fuel lean, and the oil clean.
Adding a capacitive discharge ignition might help make sure the fuel is burned more completely, but such an ignition would probably ruin the plug wires, not designed to be used with shielded wire if that's what is in place.
One thing to ask, is "how do modern day gas engines get good fuel economy", and try to apply some of those concepts where reasonable.