Yep, sounds like a wheel valve. I remove the banjo bolt on the large hose connected to the wheel stud like Simp5782 suggested, but I tape a rubber glove over the hose back to the wheel valve. If the glove inflates the wheel valve is leaking. If so, Deflate the tire and remove the 4 screws on the wheel valve and remove the cover. It has a spring and rubber diaphragm inside and may just have crap where it seals the small center hole that goes to the tire. One of mine was doing this and a good cleaning fixed it.
A really leaky tire might fault CTIS as will a tire that is radically different in pressure from the rest, but you may also have leaks elsewhere in the system. Once the wet tank is to full pressure the first thing the system does is close the control solenoid and give a shot of air with the supply solenoid to pressurize the system and open the wheel valves. Then it looks for a stable air pressure at the pressure sensor. A leak or low tire will cause an unstable pressure until the tires equalize and will fault the system.
Leaks are easier to find if you feed the truck shop air to the front emergency gladhand(chock the wheels as this releases the park brake) and can leave the engine off. It is easier still if you can remove the connector at the controller and jumper the pins on the cable end connector to energize the control solenoid and briefly energize the supply solenoid to pressurize the CTIS system. This allows you to leave the system pressurized as long as necessary to throughly look for leaks instead of waiting for the controller to briefly pressurize the system till it faults and you must reset it...