makeup of the snow makes the biggest difference. If its wet, hot spinning tires with lots of PSI can create an ice layer which can really screw you up. Drifting snow hardens like concrete and can hang up your axles, control arms if the drift is big enough. small drifts, as long as some wheel has bite will be a none issue. large drifts, large enough that your whole truck sits on it, you are screwed. light fluffy snow is no issue, my M35 waded into 34 inches of the stuff without breaking a sweat